POST-HEMIPLEGIC PARALYSIS AGITANS

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The distribution of Lewy bodies in the central and autonomic nervous systems in idiopathic paralysis agitans.

The hyaline inclusions in the pigmented ganglion cells of the substantia nigra and the locus coeruleus in patients suffering from idiopathic paralysis agitans are known as Lewy bodies after their discoverer, Lewy (1913). A detailed description of these bodies was presented by Greenfield and Bosanquet in 1953. The intracytoplasmic bodies are always surrounded by a light halo, and often have a ce...

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The Incidence and Characteristics of Lewy Bodies in Idiopathic Paralysis Agitans

In 1913, the Breslau neurologist Lewy described globular inclusions of cytoplasmic condensations in the cells of the nucleus substantiae innominatae and the dorsal vagal nucleus in paralysis agitans. These cell inclusions have since been described by many other investigators. In 1923, Lewy also found them in the pigmented ganglion cells of the substantia nigra in Parkinson's disease. Tretiakoff...

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ژورنال

عنوان ژورنال: The Lancet

سال: 1895

ISSN: 0140-6736

DOI: 10.1016/s0140-6736(01)46855-3